Detalhe da pesquisa
1.
Evaluation of the potential drug-drug interactions of carotegrast methyl with midazolam, prednisolone or atorvastatin in healthy adults.
Br J Clin Pharmacol
; 90(3): 871-881, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38030591
2.
Effects of rifampicin on the pharmacokinetics and safety of carotegrast methyl in healthy subjects: A randomized 2 × 2 crossover study.
Br J Clin Pharmacol
; 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38408756
3.
Elucidation of N 1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters.
Drug Metab Dispos
; 47(11): 1270-1280, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511257
4.
Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation.
Eur J Clin Pharmacol
; 75(3): 351-361, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30382297
5.
Pharmacokinetics and pharmacodynamics of FSK0808 and Gran after single intravenous drip administration or single subcutaneous administration: comparative study in healthy Japanese adult male subjects.
Drug Dev Ind Pharm
; 41(3): 470-5, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24471477
6.
Pharmacokinetics, safety, and tolerability of the novel tetrameric gadolinium-based MRI contrast agent gadoquatrane in healthy Chinese and Japanese men: Two randomized dose-escalation studies including concentration-QTc modeling.
Eur J Pharm Sci
; 196: 106749, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38499113
7.
Safety, Tolerability, and Pharmacokinetics of Valemetostat Tablets and the Effect of Food on Valemetostat Pharmacokinetics in Healthy Subjects: Two Phase 1 Studies.
Clin Pharmacol Drug Dev
; 13(1): 77-86, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37565616
8.
Effect of γ-tocopherol supplementation on premenstrual symptoms and natriuresis: a randomized, double-blind, placebo-controlled study.
BMC Complement Med Ther
; 23(1): 136, 2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118716
9.
Effect of itraconazole and fluconazole on the pharmacokinetics of valemetostat: An open-label, phase I study in healthy subjects.
Clin Transl Sci
; 16(11): 2153-2162, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37705321
10.
Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing.
Int J Clin Pharmacol Ther
; 50(10): 689-700, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853867
11.
Single- and Multiple-Dose Pharmacokinetics and Safety of Vilaprisan in Healthy Postmenopausal Japanese Women: A Randomized Clinical Trial.
Eur J Drug Metab Pharmacokinet
; 47(1): 49-56, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635989
12.
Effects of a reactive oxygen species generator, napabucasin (BBI608), on tolerability, safety, pharmacokinetics, and QT/QTc interval in healthy volunteers.
Pharmacol Res Perspect
; 9(5): e00874, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34628720
13.
Statistical Analysis of the Axillary Temperatures Measured by a Predictive Electronic Thermometer in Healthy Japanese Adults.
Int J Environ Res Public Health
; 18(10)2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34065809
14.
SARS-CoV-2 Seroprevalence among Healthcare Workers in General Hospitals and Clinics in Japan.
Int J Environ Res Public Health
; 18(7)2021 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33916399
15.
Cerebrospinal Fluid Protein Concentration in Healthy Older Japanese Volunteers.
Int J Environ Res Public Health
; 18(16)2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34444430
16.
A Phase 1, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Subcutaneous Tezepelumab in Healthy Japanese Men.
Clin Pharmacol Drug Dev
; 9(7): 833-840, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31960624
17.
Comparative pharmacokinetics of maxacalcitol in healthy Taiwanese and Japanese subjects.
Heliyon
; 6(3): e03538, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181403
18.
Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers.
Drug Metab Pharmacokinet
; 34(1): 78-86, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528195
19.
The Effect of Drug Content Reduction on the In Vitro and In Vivo Properties of Levonorgestrel-Releasing Intravaginal Rings.
J Pharm Sci
; 107(4): 1020-1027, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29175414
20.
Clinical Drug-Drug Interaction Potential of BFE1224, Prodrug of Antifungal Ravuconazole, Using Two Types of Cocktails in Healthy Subjects.
Clin Transl Sci
; 11(5): 477-486, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29768713